ACUTE RHINITIS
Rhinitis is the irritation and
inflammation of the mucosal surface of the nose, most commonly due to infection
with respiratory viruses.
Common symptoms of rhinitis are a
stuffy nose, runny nose, and post-nasal drip.[1]
The most common kind of rhinitis
is allergic rhinitis,[2] which is usually triggered by airborne allergens such
as pollen and dander.[3] Allergic rhinitis may cause additional symptoms, such
as sneezing and nasal itching, coughing, headache,[2] fatigue, malaise, and
cognitive impairment.[4][5][6] The allergens may also affect the eyes, causing
watery, reddened, or itchy eyes and puffiness around the eyes.[2]...continue
In rhinitis, the inflammation of
the mucous membrane is caused by viruses, bacteria, irritants or allergens. The
inflammation results in the generation of large amounts of mucus, commonly
producing a runny nose, as well as a stuffy nose and post-nasal drip. In the
case of allergic rhinitis, the inflammation is caused by the degranulation of
mast cells in the nose. When mast cells degranulate, they release histamine and
other chemicals,[7] starting an inflammatory process that can cause symptoms
outside the nose, such as fatigue and malaise.[8] In the case of infectious
rhinitis, it may occasionally lead to pneumonia, either viral pneumonia or
bacterial pneumonia. Sneezing also occurs in infectious rhinitis to expel
bacteria and viruses from respiratory system.
Types
Rhinitis is categorized into
three types:
(a) Infective rhinitis includes
acute and chronic bacterial infections;
(b) Non-allergic (vasomotor) rhinitis
includes autonomic, hormonal, drug-induced, atrophic, and gustatory rhinitis,
as well as rhinitis medicamentosa;
(c) Allergic rhinitis, triggered
by pollen, mold, animal dander, dust, Balsam of Peru, and other similar inhaled
allergens.[2]
Management
The management of rhinitis
depends on the underlying cause. High-dose administration of Vitamin B12 has
been additionally validated to stimulate the activity of the body's TH1
suppressor T-Cells, which then down-regulates the over-production of the
allergen antibody IgE in allergic individuals, which could decrease both near-
and long-term manifestations of rhinitis symptomology.[9][10]
For allergic rhinitis, intranasal
corticosteroids and antihistamines can be used to suppress inflammation and
control symptoms.
Prevention
In the case of infectious
rhinitis, vaccination against Influenza viruses, Adenoviruses, Measles,
Rubella, Streptococcus pneumoniae, Haemophilus influenzae, Diphtheria, Bacillus
anthracis, and Bordetella may help prevent it.
Treatment Objectives
Relieve nasal mucosal oedema and
obstruction
Relieve pain/discomfort
Treat complications
Drug Treatment
Analgesics e.g. Paracetamol
Anti-histamines e.g. Loratadine,
Chlopheniramine maleate (Piriton)
Antibiotics - Only if secondary
bacterial infection occurs.
Supportive Measures
Steam inhalation with a drop of
eucalyptus oil
Source: Pharma-Guide-Nigeria
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